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In the Second of our series How Covid Changed Science, Devi Sridhar Professor of Global Health at Edinburgh University looks at the scientific messaging. Just how do you explain to both politicians and the public that a growing global pandemic is likely to kill many people, and unprecedented measures such as a nationwide lockdown are needed to prevent even more deaths. What information should be imparted and how? Similarly how to address the clamour for information on the development of vaccines and other potential treatments when there often wasn’t clarity? And with the rise of misinformation how did individual scientists who became the subject of conspiracy theories cope with being targeted? In this programme we hear from scientists and politicians directly involved with the pandemic response. For some the experience of explaining their often highly technical research to the general public was a daunting experience. For others it became a mission to answer the publics concerns and fears.