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The United Nations has warned that nearly three million children could contract HIV by 2040, with more than half at risk of dying from AIDS-related illnesses if prevention and treatment efforts are not significantly expanded. The agency says the overwhelming majority of these infections are expected to occur in sub-Saharan Africa, where young people remain disproportionately affected by the epidemic. Amid these concerns, a major scientific breakthrough is offering new hope. Lenacapavir, a long-acting HIV prevention injection administered just twice a year, is being hailed as a potential game-changer, particularly for young people and others who struggle to adhere to daily prevention pills. In United States, Minnesota , the fentanyl epidemic continues to devastate families and communities, with overdose deaths leaving a lasting toll. Presenter: Nkechi Ogbonna Producers: Blessing Aderogba Technical Producer: Herbert Masua Senior Producer: Keikantse Shumba Editors: Charles Gitonga and Maryam Abdalla